Perimenopause & Type 1 Diabetes

Perimenopause & diabetes: what's really happening to your blood sugar

🇺🇦 Читати українською

Perimenopause & diabetes: what's really happening to your blood sugar

Blood sugar can get harder to manage in perimenopause — and almost no one warns you. Here's what's really happening, and what genuinely helped me.

I've been living with type 1 diabetes for 23 years. Around 39–40, I started noticing I was getting more insulin resistant — it was harder to manage my normal food. I usually make a cup of coffee in the morning with soya milk, about 4g of carbs per cup. My blood sugar started climbing to 18 mmol/l — ridiculously high for such a tiny amount of carbs.

At the gym I noticed the same pattern: my sugar stayed high throughout training and climbed even more afterwards — partly explained by the nature of resistance training, which can raise blood glucose. But getting it back into range became a real challenge. My body simply wasn't reacting the way it used to.

Lena Filatova doing a barbell squat with a continuous glucose monitor on her arm
At the gym, CGM on — where I first noticed resistance training pushing my blood sugar in ways it never used to.

I asked my diabetes team at St Barts in London what was happening. Of course I knew I was getting older, but nobody was talking about what that actually looks like in practice. They looked at my readings and said: all good, you're being too hard on yourself. But I knew exactly what it took to reach that “good” — so much more effort than before.

The medical gap nobody talks about

On work trips I had to skip meals because I couldn't risk eating something that would push me into very high blood sugars in the middle of a conference. I was starving to stay in range — constantly exhausted and hungry. Any emotion, good or bad, would send my blood sugar shooting up to 17–18 mmol/l, and I'd struggle to bring it back down.

At my next appointment I tried to raise this with my endocrinologist, but he said they don't have any training on women's health in this period of life. Because I still had regular periods, he told me I wasn't in perimenopause and didn't need anything fixing. When I brought up gaining belly fat, he said my weight was the same as last year — nothing to worry about.

I was left fighting alone.

Getting HRT prescribed was its own battle. My GP wasn't convinced that hormones affect insulin sensitivity — something so fundamental I assumed any provider would know it, given that all hormones affect each other. I'm grateful for the specialists who listened and prescribed HRT even though I still had regular cycles and no hot flushes. It changed everything. I got back a few years in my management — things were still a little harder and less predictable than before, but nowhere near as hard.

I have experience reading research papers and writing health and fitness news, so I decided to start an open conversation for women who are looking for answers, just like me.

Why blood sugar gets harder to manage in perimenopause

I recently changed my diabetes team and felt understood immediately — but even they pointed to the lack of research and information on women's health over 40 for those living with diabetes.

Insulin pump screen showing blood sugar rising to 17.7 mmol/l overnight with 7.9 units of insulin on board
A night from my own pump — blood sugar swinging up to 17.7 mmol/l with 7.9u of insulin still on board. The kind of overnight pattern that got much harder to control in perimenopause.

As oestrogen fluctuates and falls, insulin sensitivity drops. The same meals that used to keep your blood sugar steady can push it much higher, and it tends to climb more easily overall. I also noticed a pattern within my own cycles — one month would feel relatively normal and predictable, and the next my body simply wasn't producing as many hormones and I'd be far less sensitive to insulin.

This isn't a failure of your management. It's biology that the medical world is only beginning to take seriously.

What can actually help

HRT was the single biggest lever for me. If you're approaching 40 and finding your control inexplicably harder, it's worth having the conversation with a specialist who understands both hormonal health and diabetes — even if you still have regular periods and no hot flushes.

Resistance training is one of the most reliable tools for blood glucose management: building muscle improves how your body handles glucose, protects your bones, and steadies energy far better than any single supplement. That said, with sleep disruption, joint pain and blood sugar swings, even training becomes harder during perimenopause. I noticed this too. It doesn't mean stop — it means adjust.

Every decision about your management should be made together with your doctor. My goal here is to make sure you know what you might face, and what can help, so you walk into those appointments informed.

UK resources worth knowing about

If you're looking for somewhere to start, these two UK organisations have the most relevant information specifically for women with diabetes going through perimenopause.

What the research says

The medical gap is real — and only recently starting to be acknowledged in the literature. Here's where the evidence currently stands.

The menstrual cycle affects insulin sensitivity in T1D — and perimenopause amplifies it.

A 2023 systematic review in Frontiers in Endocrinology examined how the menstrual cycle affects glycaemic outcomes and insulin sensitivity in women with type 1 diabetes. It confirmed that hormonal fluctuations across the cycle do affect blood glucose, while noting major gaps in the evidence — particularly around perimenopause.

Frontiers in Endocrinology · Systematic review, 2023 ↗
There is almost no dedicated research on menopause management for women with T1D.

A 2025 narrative review in Therapeutic Advances in Endocrinology and Metabolism examined the current evidence on menopause management in women with type 1 diabetes and concluded that the research gaps are substantial — calling for targeted studies to address them.

Therapeutic Advances in Endocrinology and Metabolism · Narrative review, 2025 ↗
HRT does reduce insulin resistance — and the evidence is growing.

A 2024 meta-analysis of 17 randomised controlled trials covering more than 29,000 participants (1998–2024), presented at The Menopause Society Annual Meeting, found that hormone therapy significantly reduced insulin resistance in postmenopausal women.

The Menopause Society Annual Meeting, 2024 ↗
The field is finally catching up.

A clinical trial called TIMES (Trajectories in Insulin Sensitivity Across MEnstrual cycleS in Women With Type 1 Diabetes) began recruiting in late 2025. It aims to map exactly how insulin sensitivity changes across the cycle in women with T1D — which will help build the evidence base for perimenopause management too.

ClinicalTrials.gov — TIMES study ↗
Lena Filatova, women's health writer living with type 1 diabetes
Lena Filatova

Lena Filatova has lived with type 1 diabetes for 23 years. She writes about women's health, perimenopause and diabetes management at lenafilatova.co.uk.

Frequently asked questions

Does perimenopause affect blood sugar in type 1 diabetes?

Yes. As oestrogen levels fluctuate and decline during perimenopause, insulin sensitivity drops. The same meals and insulin doses that worked before may no longer produce the same results. Women with type 1 diabetes often experience higher blood sugar, more variability between cycles, and greater difficulty recovering from spikes — all without any obvious change in routine.

Can you be in perimenopause if you still have regular periods?

Yes. Perimenopause can begin years before periods become irregular. Hormonal fluctuations — and their effect on insulin sensitivity — can start in your late 30s or early 40s while cycles remain perfectly regular. This is one of the most misunderstood points in women's health, and a main reason so many women with diabetes go unheard for years.

Does HRT help with blood sugar control during perimenopause?

For many women with diabetes, HRT can improve insulin sensitivity as oestrogen levels stabilise, consistent with what we know about how hormones affect glucose metabolism. It isn't right for everyone, and the decision should be made with a provider who understands both your hormonal and metabolic health.

Why do I gain belly fat in perimenopause even if my weight hasn't changed?

Shifting oestrogen levels change where the body stores fat, often redistributing it towards the abdomen. This can happen even when total weight stays the same — which is why “your weight hasn't changed” isn't a satisfying or complete answer.

The information on this website is educational and is not medical advice. Please consult your doctor if you have any doubts or further questions.

← All articles